This study aims to determine the potential of creative industries for people with disabilities in Yogyakarta. By gathering data from small and medium industries (IKM), creative industries, documents, interviews, and using qualitative description approach as a method of analysis, this research finds at least five important results. Firstly, people with deaf-mute condition and physical disability can work on all types of creative industries, but mental disability and mental-physical disability can only work on certain types of industry. Secondly, craft industry is the most widely sector for people with disabilities to earn more income. Thirdly, Bantul and Gunungkidul provide many jobs opportunities in creative industries compared to other districts. Fourthly, the potential of disabled people to work in creative industries decreases from 2014 to 2015 except for Yogyakarta City. The last one, job opportunity for people with disabilities may potentially be increased by expanding the type of business in Yogyakarta.